Role of Extracellular Matrix in Three-dimensional Muscle Cell Culture
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چکیده
منابع مشابه
Retinoic acid attenuates cytokine-driven fibroblast degradation of extracellular matrix in three-dimensional culture.
Proteolytic degradation of extracellular matrix is thought to play an important role both in emphysema and in tissue development and repair. Retinoic acid has been suggested to modify tissue injury, and in an animal model of emphysema may induce alveolar repair. Since cytokines can induce matrix metalloproteinase (MMP) production in fibroblasts and neutrophil elastase (NE) can activate MMPs, we...
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Skeletal muscle fibers are surrounded by an extracellular matrix. The extracellular matrix is composed of glycoproteins, collagen, and proteoglycans. Proteoglycans have been suggested to play an important functional role in tissue differentiation; however, an understanding of how the extracellular matrix affects skeletal muscle development and function is largely unknown. Proteoglycans can regu...
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ژورنال
عنوان ژورنال: Juntendo Medical Journal
سال: 2020
ISSN: 2187-9737,2188-2126
DOI: 10.14789/jmj.2020.66.jmj19-re02